Lab. of Neurophysiology. Seoul National Univ.

64. Junghwa Lee & Sukwoo Choi. Protocols for 'delayed safety-seeking behavior' in rats. Star Protocols(2024) (in press)

63. Yujin Han, Kuenbae Sohn, Donghyeon Yoon, Sewon Park, Junghwa Lee*, Sukwoo Choi*. Delayed escape behavior requires claustral activity. Cell Reports(2024) 43(2):113748. *corresponding author

62. Junghwa Lee, Bobae An*, Sukwoo Choi*. Longitudinal recordings of single units in the basal amygdala during fear conditioning and extinction. Scientific Reports, (2020) 11, 11177 *corresponding author

61. Sukwoon Song, Jihye Kim, Kyungjoon Park, Junghwa Lee, Sewon Park, Sukwon Lee, Jeongyeon Kim, Ingie Hong, Beomjong Song, Sukwoo Choi. GSK-3β activation is required for ZIP-induced disruption of learned fear. Scientific Reports>, (2020) 10, 18227

60. Sewon Park, Sukwoo Choi. Initial conditioning and reconditioning recruit different populations of 'fear neurons' in the basal amygdala of rats. Biochemical and Biophysical Research Communications, (2020) 525(2):292-297.

59. Sukwoon Song, Junghwa Lee, Sewon Park, Sukwoo Choi. Fear renewal requires nitric oxide signaling in the lateral amygdala. Biochemical and Biophysical Research Communications, (2019) 523(1):86-90.

58. Sukwon Lee, Jeongyeon Kim, Sukwoo Choi. Endogenous Amyloid-ß Mediates Memory Forgetting in the Normal Brain. Biochemical and Biophysical Research Communications, (2018) 506(3):492-497.

57. Sungdae Kim, Minyeop Nahm, Najin Kim, Yumi Kwon, Joohyung Kim, Sukwoo Choi, Eun Young Choi, Jiwon Shim, Cheolju Lee, and Seungbok Lee. Graf regulates hematopoiesis through GEEC endocytosis of EGFR. Development, (2017) 144(22):4159-4172.

56. Bobae An, Jihye Kim, Kyungjoon Park, Sukwon Lee, Sukwoon Song, Sukwoo Choi* . Amount of fear extinction changes its underlying mechanisms. eLife(2017) ;6:e2522 *corresponding author,

55. Chae-Seok Lim, Xi Kang, Vincent Mirabella, Huaye Zhang, Qian Bu, Yoichi Araki, Elizabeth T. Hoang Shiqiang Wang, Ying Shen, Sukwoo Choi , Bong-Kiun Kaang, Qiang Chang, Zhiping P. Pang, Richard L. Huganir, J. Julius Zhu*. BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method. Genes & Development(2017) 31, 537-552; *corresponding author

54. Jae Young Yoon, Sukwoo Choi*. Evidence for presynaptically silent synapses in the immature hippocampus. Biochemical and Biophysical Research Communications(2017), 482, 1375-1380;, *corresponding author

53. Yujin Han#, Bobae An#, Sukwoo Choi*. Enhanced theta synchronization correlates with the successful retrieval of trace fear memory. Biochemical and Biophysical Research Communications (2016) #These authors equally contributed, *corresponding author 480(4):608-614.,

52. Sungmo Park#, Junuk Lee#, Kyungjoon Park#, Jeongyeon Kim, Beomjong Song, Ingie Hong, Jieun Kim, Sukwon Lee*, Sukwoo Choi*. Sound tuning of amygdala plasticity in auditory fear conditioning. Scientific Reports(2016) 6, 31069;, *co-corresponding author

51. Sukwoo Choi, Bobae An., Pharmaceutical Composition Comprising Inhibitors of Phosphorylation of GluA1 Subunit of AMPA receptor for preventing or treating mental disorders, Korean Intellectual Property Office (2016)

50. Sukwoo Choi, Sukwon Lee, Jeongyeon Kim, Beomjong Song, Ingie Hong, Sungmo Park, Jihye Kim, Junuk Lee, Bobae An., Pharmaceutical composition for treating anxiety disorder, containing N-acetyl-L-cysteine or derivative therof , European Patent Office (2016)

49. Sukwoo Choi, Sukwon Lee, Jeongyeon Kim, Beomjong Song, Ingie Hong, Sungmo Park, Jihye Kim, Junuk Lee, Bobae An., Pharmaceutical composition for treating anxiety disorder, containing N-acetyl-L-cysteine or derivative therof , United States Patent and Trademark Office (2016)

48. Jihye Kim, Bobae An, Jeongyeon Kim, Sewon Park, Sungmo Park, Ingie Hong, Sukwon Lee, Kyungjoon Park, Sukwoo Choi., mGluR2/3 in the lateral amygdala is required for fear extinction: cortical input synapses onto the lateral amygdala as a target site of the mGluR2/3 action , Neuropsychopharmachology (2015) 40, 2916–2928

47. Sukwoo Choi, Sukwon Lee, Jeongyeon Kim, Beomjong Song, Ingie Hong, Sungmo Park, Jihye Kim, Junuk Lee, Bobae An., Pharmaceutical composition containing GluR2-lacking AMPAR antagonist for preventing or treating psychiatric illnesses , European Patent Office (2014)

46. Kyungjoon Park, Sukwoon Song, Ingie Hong, Beomjong Song, Jeongyeon Kim, Sungmo Park, Junuk Lee, Sangho Song, Bobae An, Jihye Kim, C Justin Lee, Ki Soon Shin, Sukwoo Choi, Sukwon Lee., Group I mGluR-dependent depotentiation in the lateral amygdala does not require the removal of calcium-permeable AMPA receptors , Frontiers in Behavioral Neuroscience (2014) 8:269.

45. Sukwoo Choi, Sukwon Lee, Jeongyeon Kim, Beomjong Song, Ingie Hong, Sungmo Park, Jihye Kim, Junuk Lee, Bobae An., Pharmaceutical composition containing GluR2-lacking AMPAR antagonist for preventing or treating psychiatric illnesses United States Patent and Tradmark Office (2014)

44. Sukwoo Choi, Sukwon Lee, Jeongyeon Kim, Beomjong Song, Ingie Hong, Sungmo Park, Jihye Kim, Junuk Lee, Bobae An., Pharmaceutical composition for treating anxiety disorder, containing N-acetyl-L-cysteine or derivative therof , Korean Intellectual Property Office (2014)

43. Kyungjoon Park†, Beomjong Song†, Jeongyeon Kim†, Ingie Hong†, Sangho Song†, Junuk Lee†, Sungmo Park, Jihye Kim, Bobae An, Hyun Woo Lee, Seungbok Lee, Hyun Kim, Justin C. Lee, Sukwon Lee1,‡, Choi S‡., ABA renewal involves enhancements in both GluA2-lacking AMPA receptor activity and GluA1 phosphorylation in the lateral amygdala, Plos One (2014) (‡: co-corresponding authors)

42. Kim W, Im MJ, Park CH, Lee CJ, Choi S†, Yoon BJ†. Remodeling of the dendritic structure of the striatal medium spiny neurons accompanies behavioral recovery in a mouse model of Parkinson's disease. Neuroscience Letters (2013). 17;557 (†: co-corresponding authors) 28, Oct

41. Sukwon Lee†, Beomjong Song†, Jeongyeon Kim†, Kyungjoon Park, Ingie Hong, Bobae An, Sangho Song, Jiwon Lee, Sungmo Park, Jihye Kim, Dongeun Park, C. Justin Lee, Kyungjin Kim‡, Ki Soon Shin‡, Richard W. Tsien, Sukwoo Choi‡ GluA1 phosphorylation at Serine 831 in the lateral amygdala is required for fear renewal Nature Neuroscience (2013) 16, 1436-1444

40. Tae-In Kam, Sungmin Song, Youngdae Gwon, Hyejin Park, Ji-Jing Yan, Isak Im, Ji-Woo Choi, Tae-Yong Choi, Jeongyeon Kim, Dong-Keun Song, Toshiyuki Takai, Yong-Chul Kim, Key-Sun Kim, Se-Young Choi, . Sukwoo Choi, William L. Klein, Junying Yuan and Yong-Keun Jung FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer’s disease J Clin Invest. (2013) 123(7):2791-2802

39. Ingie Hong1,Jeongyeon Kim1, Jihye Kim1, Hyoung-Gon Ko, Sukwon Lee, Karim Nader, Bong-Kiun Kaang, Richard W. Tsien* and Choi S* AMPA receptor exchange underlies transient memory destabilization upon retrieval Proc Natl Acad Sci USA. (2013) May 14. (*co-corresponding authors)

38. Ingie Hong, Taewook Kang, YongCheol Yoo, Royun Park, Junuk Lee, Sukwon Lee, Jeongyeon Kim, Boemjong Song, Se-Young Kim, Minho Moon, Ki Na Yun, Jin Young Kim, Inhee Mook-Jung*, Young Mok Park* and Choi S* Quantitative proteomic analysis of the hippocampus in the 5XFAD mouse model at early stages of Alzheimer’s Disease pathology Journal of Alzheimer’s Disease (2013) Apr 9.

37. Ingie Hong, Taewook Kang, Ki Na Yun, YongCheol Yoo, Sungmo Park, Jihye Kim, Bobae An, Sukwoon Song, Sukwon Lee, Jeongyeon Kim, Beomjong Song, Kyung-Hoon Kwon, Jin Young Kim*, Young Mok Park* and Choi S*,Quantitative Proteomics of Auditory Fear Conditioning Biochemical and Biophysical Research Communications (2013) Apr 26

36. Han K, Woo J, Park H, Yoon B, Choi S*, and Lee CJ*. Channel-mediated astrocytic glutamate release via Bestrophin-1 targets synaptic NMDARs Molecular Brain (2013) Jan 16;6:4 (*co-corresponding authors)

35. Song B, Lee S, Choi S. LY404187, a potentiator of AMPARs, enhances both the amplitude and 1/CV2 of AMPA EPSCs but not NMDA EPSCs at CA3-CA1 synapses in the hippocampus of neonatal rats Neurosci Lett (2012) Dec 7;531(2):193-7

34. Yeo H, Kim H, Mo J, Lee D, Han S, Hong S, Koh MJ, Sun W, Choi S, Rhyu IJ, Kim H, and Lee HW. Developmental expression and subcellular distribution of synaptotagmin 11 in rat hippocampus. Neurosci (2012) Dec 6;225:35-43 .

33. Park S, Kim J, Choi S Ex vivo depotentiation of conditioning-induced potentiation at thalamic input synapses onto the lateral amygdala requires GluN2B-containing NMDA receptors. Neurosci Lett (2012) Nov 21;530(2):121-6

32. An B, Hong I, Choi S Long-term neural correlates of reversible fear learning in the lateral amygdala. J Neurosci (2012) 21 Nov. 32(47): 16845-16856

31. Mo J, Lee D, Hong S, Han S, Yeo H, Sun W, Choi S, Kim H, Lee HW (2012) Preso regulation of dendritic outgrowth through PI(4,5)P 2-dependent PDZ interaction with βPix. Eur J Neurosci 36 (1): 1960-1970

30. Mo J, Choi S, Ahn PG, Sun W, Lee HW, Kim H (2012) PDZ-scaffold protein, Tamalin promotes dendritic outgrowth and arborization in rat hippocampal neuron. Biochem Biophys Res Comm 422 (2):250-255

29. Lee S, Ahmed T, Lee S, Kim H, Choi S , Kim D, Kim SJ, Cho J, Shin H (2012) Bidirectional modulation of fear extinction by mediodorsal thalamic firing in mice. Nat Neurosci 15 (2):308-314

28. Hong I, Kim J, Song B, Park K, Shin K, Eom KD, Han PL, Lee S, Choi S (2012) Fear conditioning occludes late-phase long-term potentiation at thalamic input synapses onto the lateral amygdala in rat brain slices. Neurosci Lett 506 (1):121-125

27. Hong I, Kim J, Park S, Lee J, Song B, Kim J, An B, Park K, Lee HW, Lee S, Kim H, Park SH, Eom KD, Lee S#, Choi S# (2011) Reversible plasticity of fear memory-encoding amygdala synaptic circuits even after fear memory consolidation (# co-corresponding author) PloS One (9):e24260 Sep 19

26. EJ Lee*, GH Son*, SY Chung, SW Lee, JY Kim, SW Choi#, and KJ Kim# (2011) Impairment of Fear Memory Consolidation in Maternally Stressed Male Mouse Offspring: Evidence for Nongenomic Glucocorticoid Action on the Amygdala (# co-corresponding author) J. Neurosci. 31(19):7131–7140

25. Lee S, Kim J, Choi S. (2011) In vitro synaptic reconsolidation in amygdala slices prepared from rat brains. Biochem Biophys Res Commun. 30(28):9631-40.

24.Hong I,Kim J, Song B, Park S, Lee J, Kim J, An B, Lee S, Choi S. (2011) Modulation of fear memory by retrieval and extinction: a clue for memory consolidation Rev. Neurosci. 22(2):205-29

23. Kim J, Song B, Hong I, Kim J, Lee J, Park S, Eom JY, Lee CJ, Lee S, Choi S. (2010) Reactivation of fear memory renders consolidated amygdala synapses labile. J. Neurosci. 30(28):9631-40.

22. Kim J, Park S, Lee S, Choi S. (2009) Amygdala depotentiation ex vivo requires mitogen-activated protein kinases and protein synthesis. Neuroreport 20 / 517-20.

21. Hong I, Song B, Lee S, Kim JH, Kim JY, Choi S. (2009)Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala. European J. Neurosci

20. Kim WR, Park OH, Choi S, Choi SY, Park SK, Lee KJ, Rhyu IJ, Kim H, Lee YK, Kim HT, Oppenheim RW, Sun W. (2009)The maintenance of specific aspects of neuronal function and behavior is dependent on programmed cell death of adult-generated neurons in the dentate gyrus. European J. Neurosci

19. Son GH, Chung S, Choe HK, Kim HD, Baik SM, Lee H, Lee HW, Choi S, Sun W, Kim H, Cho S, Lee KH, Kim K. (2008) Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production. Proc Natl Acad Sci USA. 105(52):20970-5.

18. Kim J, Lee S, Park K, Hong I, Song B, Son G, Park H, Kim WR, Park E, Choe HK, Kim H, Lee C, Sun W, Kim K, Shin KS, Choi S. (2007) Amygdala depotentiation and fear extinction. Proc Natl Acad Sci USA. 26 / 20955-60.

17. Park K, Lee S, Kang SJ, Choi S, Shin KS. (2007)Hyperpolarization-activated currents control the excitability of principal neurons in the basolateral amygdala. Biochem Biophys Res Commun. 28 / 718-24.

16. Kim J, Lee S, Park H, Song B, Hong I, Geum D, Shin K, Choi S. (2007) Blockade of amygdala metabotropic glutamate receptor subtype 1 impairs fear extinction.
Biochem Biophys Res Commun. 30 / 188-93.

15. Son GH, Chung S, Geum D, Kang SS, Choi WS, Kim K, Choi S. (2006) Hyperactivity and alteration of the midbrain dopaminergic system in maternally stressed male mice offspring. Biochem Biophys Res Commun. 352(3) / 823-9.

14. Son GH, Geum D, Chung S, Kim EJ, Jo JH, Kim CM, Lee KH, Kim H, Choi S, Kim HT, Lee CJ, Kim K. (2006) Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity.
J Neurosci. 26(12) / 3309-18.

13. Harata NC, Choi S, Pyle JL, Aravanis AM, Tsien RW (2006) Frequency-dependent kinetics and prevalence of kiss-and-run and reuse at hippocampal synapses studied with novel quenching methods. Neuron 49 / 243-56

12. Son GH, Geum D, Chung S, Park E, Lee KH, Choi S, Kim K. (2005) A protective role of 27-kDa heat shock protein in glucocorticoid-evoked apoptotic cell death of hippocampal progenitor cells. Biochem Biophys Res Commun. 338(4) / 1751-8.

11. Park EJ, Nam RH, Choi S, Lee CJ (2004) Carbachol induces a form of long-term potentiation in lateral amygdala. Neuroreport 15 / 1339-43

10. Choi S, Klingauf J, Tsien RW (2003) Fusion pore modulation as a presynaptic mechanism contributing to expression of long-term potentiation. Philos Trans R Soc Lond B Biol Sci 358 / 695-705

9. Park EJ, Suh YH, Kim JY, Choi S, Lee CJ (2003) Long-lasting facilitation by dehydroevodiamine. HClof synaptic responses evoked in the CA1 region of rat hippocampal slices. Neuroreport 14 / 399-403

8. Lee O, Lee CJ, Choi S (2002) Induction mechanisms for L-LTP at thalamic input synapses to the lateral amygdala: requirement of mGluR5 activation. Neuroreport 13 / 685-91

7. Lee SC, Choi S, Lee T, Kim HL, Chin H, Shin HS (2002) Molecular basis of R-type calcium channels in central amygdala neurons of the mouse. Proc Natl Acad Sci USA 99 / 3276-81

6. Sung KW, Choi S, Lovinger DM (2001) Activation of group I mGluRs is necessary for induction of long-term depression at striatal synapses. J Neurophysiol 86 / 2405-12

5. Choi S, Klingauf J, Tsien RW (2000) Postfusional regulation of cleft glutamate concentration during LTP at 'silent synapses'. Nat Neurosci 3 / 330-6

4. Choi S, Lovinger DM (1997) Decreased frequency but not amplitude of quantal synaptic responses associated with expression of corticostriatal long-term depression. J Neurosci 17 / 8613-20

3. Strack S, Choi S, Lovinger DM, Colbran RJ (1997) Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density. J Biol Chem 272 / 13467-70

2. Choi S, Lovinger DM (1997) Decreased probability of neurotransmitter release underlies striatal long-term depression and postnatal development of corticostriatal synapses. Proc Natl Acad Sci USA 94 / 2665-70

1. Choi S, Lovinger DM (1996) Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons. J Neurosci 16 / 36-45

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